Welcome to pH Buffer Calculator! 🧪

First time here? Perfect! Let's get you started in 30 seconds.

🟢 Beginner

Just the basics - perfect to start! Simple buffer calculator with 3 common buffers.

🟡 Intermediate

More control! Access to 6 buffer systems and advanced parameters.

🔴 Expert

Full power! All buffers, temperature corrections, ionic strength adjustments.

🧪 pH Buffer Calculator

Design perfect buffer solutions instantly! Calculate concentrations, prepare recipes, and optimize your experiments with AI assistance.

🤔

What Is a pH Buffer?

Think of a bouncer at a club - buffers keep pH stable no matter what tries to crash the party!

Buffer solutions resist pH changes when acids or bases are added, essential for maintaining stable conditions in biological and chemical systems. They work through chemical equilibrium between weak acids and their conjugate bases.

🩸
Blood Chemistry
Maintains blood pH at 7.4±0.05 for survival
🧬
DNA/RNA Research
Critical for extraction and purification protocols
💊
Drug Development
Ensures stable pH in pharmaceutical formulations
🦠
Cell Culture
Maintains optimal pH for cell growth in media
🔬
Enzyme Studies
Preserves enzyme activity at specific pH ranges
🏭
Food Industry
Controls pH in food processing and preservation
Select Difficulty:

Quick Start

🎛️ Basic Parameters

pH: 7.4

Buffer Visualization

pH: 7.4

🧪 Try Common Buffer Examples

🩸
PBS
pH 7.4
🧬
TAE
pH 8.3
TBE
pH 8.3
🍋
Citrate
pH 6.0
🫧
Carbonate
pH 9.2
🔬
Glycine
pH 10.0

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d="diffIntermediate" onclick="setDifficulty('intermediate')"> 🟡 Intermediate